drugset / Trial / NCT06388564
A Study to Evaluate the Safety and Efficacy of Axatilimab in Combination With Ruxolitinib in Participants With Newly Diagnosed Chronic Graft-Versus-Host Disease
RandomizedParallel-groupOpen-labelTreatment
Summary
This study will be conducted to determine the preliminary efficacy of axatilimab in combination with ruxolitinib and to assess the contribution of axatilimab to the combination treatment effect in participants with cGVHD.
Timeline
- Start
- 2024-10-11
- Primary completion
- 2027-06-01
- Completion
- 2029-12-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Axatilimab | Monoclonal antibody | — | — |
| Subject | Methylprednisolone | Other / unclassified | — | — |
| Subject | Prednisolone | Other / unclassified | — | — |
| Subject | Prednisone | Other / unclassified | — | — |
| Subject | Ruxolitinib | Small molecule | — | — |