drugset / Trial / NCT06390059

EF-39 PANOVA-4: Study of Tumor Treating Fields Concomitant With Atezolizumab, Gemcitabine and Nab-Paclitaxel as First-LineTreatment for Metastatic Pancreatic Ductal Adenocarcinoma

NCT06390059 ↗

Phase 2 Completed 84 enrolled NovoCure Ltd.
NaSingle-groupOpen-labelTreatment

Summary

The PANOVA-4 study is designed to evaluate the safety and efficacy of Tumor Treating Fields (TTFields) therapy together with atezolizumab, gemcitabine and nab-paclitaxel, for the treatment of metastatic pancreatic cancer. The study is intended for patients who have been diagnosed with metastatic pancreatic cancer and have not received prior systemic therapy.

Timeline

Start
2023-08-28
Primary completion
2025-11-18
Completion
2025-11-18

Drugs

EvaluationDrugModalityDoseRoute
Subject Atezolizumab Monoclonal antibody — Intravenous
Background Gemcitabine Small molecule — Intravenous
Background Nab-paclitaxel Small molecule — Intravenous