drugset / Trial / NCT06395103

Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

NCT06395103

Phase 1/2 Recruiting 90 enrolled Merck Sharp & Dohme LLC
NaSingle-groupOpen-labelTreatment

Summary

Substudy 01A is part of a platform study. The purpose of this study is to assess the efficacy and safety of zilovertamab vedotin in pediatric participants with relapsed or refractory B-cell acute lymphoblastic leukemia (B-ALL), diffuse large B-cell lymphoma (DLBCL)/Burkitt lymphoma, or neuroblastoma and in pediatric and young adult participants with Ewing sarcoma.

Timeline

Start
2024-08-16
Primary completion
2029-03-31
Completion
2029-03-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Zilovertamab vedotin Unknown Intravenous