drugset / Trial / NCT06403046

Does Successive Intra-articular Injections of Tenoxicam or Meloxicam Affect Treatment of TMJ Displacement

NCT06403046

Phase 1/2 Completed 30 enrolled Beni-Suef University
RandomizedSequentialDouble-blindTreatment

Summary

The temporomandibular joint's (TMJ) articular disc, situated between the mandibular condyle's convexity and the articular tubercle's slope, is the most intricate synovial articulation in the human body. While the usual discal position as defined by magnetic resonance imaging (MRI) places the posterior discal band at the 12 o'clock position atop the mandibular condyle's maximum convexity, this discal disposition is altered in over 30% of the population without any accompanying physical symptoms. This denotes that rather than correcting the anatomical disc position, the treatment for discal displacement would primarily focus on symptom relief.

Timeline

Start
2024-06-01
Primary completion
2025-05-07
Completion
2025-09-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Meloxicam Small molecule Other
Subject Tenoxicam Other / unclassified Other