drugset / Trial / NCT06416800
A Study to Assess the Effect of Povorcitinib on Digoxin, Rosuvastatin, and Metformin Pharmacokinetics and the Effect of Probenecid on Povorcitinib Pharmacokinetics When Administered Orally to Healthy Adult Participants
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to Assess the Effect of Povorcitinib on Digoxin, Rosuvastatin, and Metformin Pharmacokinetics and the Effect of Probenecid on Povorcitinib Pharmacokinetics When Administered Orally to Healthy Adult Participants.
Timeline
- Start
- 2024-06-19
- Primary completion
- 2025-01-15
- Completion
- 2025-01-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Digoxin | Other / unclassified | — | Oral |
| Subject | Metformin | Small molecule | — | Oral |
| Subject | Povorcitinib | Small molecule | — | Oral |
| Subject | Probenecid | Small molecule | — | Oral |
| Subject | Rosuvastatin | Small molecule | — | Oral |
Indications
No indication recorded.