drugset
drugset / Trial / NCT06418893

Effect of TCI Propofol on Liver Transplant (TCI) Propofol on Intra-operative Usage of Vasopressors in Liver Transplant Recipients.

NCT06418893 ↗

Phase 2/3 Unknown 60 enrolled Institute of Liver and Biliary Sciences, India Institute of Liver and Biliary Sciences · collab
RandomizedParallel-groupTriple-blindPrevention

Summary

Both isoflurane and propofol are being used to give anaesthesia for living donor liver transplant in our institute. Propofol when compared to isoflurane has advantages like early awakening from anaesthesia, reduced nausea, vomiting in the postoperative period. Propofol also has antioxidant properties. Because of its antioxidant properties propofol may have a protective effect against oxidative stress and ischemia reperfusion injury in major organs during liver transplant surgery. However, there are no studies showing the effect of isoflurane and propofol on Intraoperative hemodynamics and postoperative liver and kidney functions.Thus, we are conducting this study to know the effect of these agents on intraoperative hemodynamics and postoperative liver and kidney function.

Timeline

Start
2023-08-01
Primary completion
2024-10-01
Completion
2024-10-31

Drugs

EvaluationDrugModalityDoseRoute
Comparator Isoflurane Other / unclassified — Inhaled
Subject Propofol Small molecule 2.5 ug/ml Intravenous

Indications

No indication recorded.