drugset / Trial / NCT06429904

Nimotuzumab Plus NALIRIFOX in Locally Advanced Pancreatic Cancer

NCT06429904

Phase 2 Active not recruiting 31 enrolled Peking Union Medical College Hospital
NaSingle-groupOpen-labelTreatment

Summary

This is a prospective, open-label, single arm clinical study. The main purpose of the study is to evaluate the clinical efficacy and safety of Nimotuzumab combined with NALIRIFOX in the treatment of locally advanced pancreatic cancer (LAPC).

Timeline

Start
2024-05-15
Primary completion
2027-05
Completion
2027-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Irinotecan Small molecule 50 mg/m2 Intravenous
Subject Leucovorin Small molecule 400 mg/m2 Intravenous
Subject Nimotuzumab Monoclonal antibody 400 mg
Subject Oxaliplatin Small molecule 60 mg/m2 Intravenous
Subject fluorouracil Small molecule 2400 mg/m2 Intravenous

Indications