drugset / Trial / NCT06442436

A Study of Nemtabrutinib in Participants With Moderate Hepatic Impairment (MK-1026-015)

NCT06442436

Phase 1 Recruiting 32 enrolled Merck Sharp & Dohme LLC
Non-randomizedSequentialOpen-labelTreatment

Summary

The purpose of this study is to compare the plasma pharmacokinetics (PK) of nemtabrutinib (MK-1026) following a single oral dose of nemtabrutinib in participants with moderate hepatic impairment to that of healthy matched control participants and to evaluate the safety and tolerability of nemtabrutinib.

Timeline

Start
2024-07-24
Primary completion
2026-09-14
Completion
2026-09-14

Drugs

EvaluationDrugModalityDoseRoute
Subject Nemtabrutinib Other / unclassified 25 mg Oral

Indications

No indication recorded.