drugset / Trial / NCT06442709
Combined Anti-IL6R and Anticoagulation Therapy in Advanced NPC Patients
RandomizedParallel-groupSingle-blindTreatment
Summary
The investigators have demonstrated the crucial role of the liver-lung axis in the distant metastasis of NPC. Furthermore, the investigators have identified a potential therapeutic approach to improve outcomes in NPC patients by identifying those most suitable for anticoagulant therapy. Further, the combination of anticoagulant therapy and anti-IL6R therapy has shown promising results in enhancing the prognosis of NPC patients. These findings highlight the significance of targeting the liver-lung axis and utilizing personalized treatment strategies for NPC.
Timeline
- Start
- 2021-08-01
- Primary completion
- 2024-07-01
- Completion
- 2024-07-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Aspirin | Small molecule | 100 mg | Oral |
| Subject | Tocilizumab | Monoclonal antibody | 4 mg/kg | Other |