drugset / Trial / NCT06442709

Combined Anti-IL6R and Anticoagulation Therapy in Advanced NPC Patients

NCT06442709

RandomizedParallel-groupSingle-blindTreatment

Summary

The investigators have demonstrated the crucial role of the liver-lung axis in the distant metastasis of NPC. Furthermore, the investigators have identified a potential therapeutic approach to improve outcomes in NPC patients by identifying those most suitable for anticoagulant therapy. Further, the combination of anticoagulant therapy and anti-IL6R therapy has shown promising results in enhancing the prognosis of NPC patients. These findings highlight the significance of targeting the liver-lung axis and utilizing personalized treatment strategies for NPC.

Timeline

Start
2021-08-01
Primary completion
2024-07-01
Completion
2024-07-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Aspirin Small molecule 100 mg Oral
Subject Tocilizumab Monoclonal antibody 4 mg/kg Other