drugset / Trial / NCT06450925

Vitamin A Supplementation in Allogeneic Stem Cell Transplantation.

NCT06450925

Phase 2 Recruiting 190 enrolled Children's Hospital Medical Center, Cincinnati
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The investigators hypothesize that single oral high dose supplementation with vitamin A will reduce the incidence of moderate-severe chronic graft-versus-host disease (GVHD) compared with placebo.

Timeline

Start
2025-03-25
Primary completion
2027-08
Completion
2029-08

Drugs

EvaluationDrugModalityDoseRoute
Comparator Vitamin A Unknown 1.2 mg/kg Oral