drugset / Trial / NCT06470373

A Phase 3 Clinical Trial to Compare RBS-001 to Eylea® in Subjects With Neovascular Age-Related Macular Degeneration

NCT06470373

Phase 3 Not yet recruiting 434 enrolled Rophibio, Inc.
RandomizedParallel-groupDouble-blindTreatment

Summary

This clinical study is designed to demonstrate the equivalence of the two Investigational Products by comparing the efficacy, safety, tolerability and immunogenicity of RBS-001 and Eylea® in subjects with Neovascular age-related macular degeneration.

Timeline

Start
2025-07
Primary completion
2026-09
Completion
2026-09

Drugs

EvaluationDrugModalityDoseRoute
Comparator Aflibercept Protein / enzyme biologic 0.05 ml Intravitreal
Comparator Aflibercept Protein / enzyme biologic 2 mg Intravitreal
Comparator RBS-001 Unknown 0.05 ml Intravitreal
Comparator RBS-001 Unknown 2 mg Intravitreal