drugset / Trial / NCT06473896

Effect of Ketalar or Dexmedetomidine on Increased Sensitivity to Pain Following Treatment With Remifentanil

NCT06473896 ↗

Recruiting 90 enrolled Assaf-Harofeh Medical Center
RandomizedParallel-groupSingle-blindTreatment

Summary

Analgesia is one of the pillars of anesthesia. One of the common opiates for pain relief, with a short half-life, is Remifentanil. However, following Remifentanil treatment an increased sensitivity to pain \[hyperalgesia\] appears. The aim of the study is to compare the effects between complementary treatments, like Ketalar and Dexmedetomidine, in preventing increased sensitivity to pain after Remifentanil treatment

Timeline

Start
2024-04-18
Primary completion
2026-04-30
Completion
2026-08-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Dexmedetomidine Other / unclassified 0.3 ug/kg —
Comparator Ketamine Small molecule 5 ug/kg —

Indications

No indication recorded.