N-Acetyl Cysteine Effect on Liver Function After Mitral Valve Replacement

Summary

This study aimed at the impact of the N-acetyl cysteine on the improvement of liver function subsequently on-pum mitral valve replacement. Following a clinical trial design, 54 candidates of on-pump MVR, aged 18 to 70 years, with normal liver and renal function were selected. The candidates were randomly divided into intervention: IV150 mg/ kg N-acetyl cysteine over 15 min, and control groups (normal saline as placebo) (n = 27 in each group).

Timeline

Start

2024-06-30

Primary completion

2024-11-30

Completion

2024-12-30

Drugs

Indications