drugset / Trial / NCT06490068

Study of LTC004 Combine With Toripalimab in Patient With Solid Tumors Resistant to Immunotherapy

NCT06490068

NaSingle-groupOpen-labelTreatment

Summary

To evaluate the efficacy and safety of LTC004 in combination with Toripalimab in 10 patients with advanced solid tumors resistant to first-line immunotherapy, all eligible subjects will receive LTC004 on day 1 of Week 1 and day 1 of week 3. Beginning at week 5, all subjects will receive LTC004 in combination with Toripalimab regimen until disease progression, intolerance, informed withdrawal or up to 2 years of dosing, whichever occurred first.

Timeline

Start
2024-06-04
Primary completion
2026-03-31
Completion
2026-03-31

Drugs

EvaluationDrugModalityDoseRoute
Subject LTC004 Unknown 45 ug/kg Intravenous
Subject Toripalimab Monoclonal antibody 240 mg Intravenous

Indications