drugset / Trial / NCT06490718
Comparing Quality of Recovery Between ESPB and IV Lidocaine After Major Breast Cancer Surgery
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The erector spinae plane block (ESPB) is gaining popularity as a regional anesthetic technique for major breast cancer surgery. Although there is controversy about its mechanism of action, emerging evidence suggests that clinical analgesia observed after ESPB in breast surgery may be due to rapid and sustained local anesthetic absorption from the injection site. Hence intravenous LA infusion (IVLI) during the perioperative period could offer an effective alternative to invasive ESPB.
Timeline
- Start
- 2024-10-25
- Primary completion
- 2025-07-17
- Completion
- 2025-07-20
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Lidocaine | Other / unclassified | 2 % | Intravenous |
| Subject | Lidocaine | Other / unclassified | 30 ml | Intravenous |
| Comparator | Ropivacaine | Other / unclassified | 0.5 % | Other |
| Comparator | Ropivacaine | Other / unclassified | 25 ml | Other |