drugset / Trial / NCT06500884

A Study to Evaluate Preventive Treatments for GPRC5D-related Oral Events

NCT06500884

Phase 2 Recruiting 210 enrolled Janssen Research & Development, LLC
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to identify preventive treatments that can minimize the occurrence, severity, and duration of talquetamab-related taste changes (dysgeusia), during the prophylaxis (preventive) treatment phase, to better characterize the signs or symptoms of talquetamab-related taste changes and to better characterize the signs or symptoms of ramantamig-related taste changes.

Timeline

Start
2024-08-26
Primary completion
2030-05-30
Completion
2030-05-30

Drugs

EvaluationDrugModalityDoseRoute
Subject JNJ-79635322 Unknown Subcutaneous
Subject Talquetamab Monoclonal antibody Subcutaneous

Indications