drugset / Trial / NCT06505187
Celecoxib for ENT Pain Management
RandomizedParallel-groupSingle-blindSupportive care
Summary
The goal of this clinical trial is to find out whether pain can be managed after an operation with celecoxib instead of oxycodone. The main question it aims to answer is if use of celecoxib plus Tylenol reduces the need for oxycodone. Researchers will compare the combination of celecoxib and Tylenol to a placebo to find out whether celecoxib works to manage pain. Participants will: * Take celecoxib, or a placebo, plus Tylenol with opioids as needed * Keep a diary of their pain between visits * Complete questionnaires
Timeline
- Start
- 2025-02-28
- Primary completion
- 2026-09
- Completion
- 2026-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Celecoxib | Other / unclassified | 200 mg | — |
| Background | Acetaminophen | Small molecule | 650 mg | — |
| Background | Oxycodone | Other / unclassified | 5 mg | — |
Indications
No indication recorded.