drugset / Trial / NCT06513923
Comparison of Remimazolam and Propofol on Emergence in Elderly Orthopedic Patients Under General Anesthesia
RandomizedParallel-groupTriple-blindPrevention
Summary
Purpose: This study aims to compare the emergence time among three anesthesia regimens: remimazolam, remimazolam with flumazenil, and propofol in elderly patients undergoing hip replacement surgery. Background: Previous studies have shown that flumazenil accelerates emergence time when used with remimazolam. Remimazolam and propofol have comparable emergence times, although remimazolam can be up to 5 minutes longer than propofol.
Timeline
- Start
- 2023-02-01
- Primary completion
- 2023-09-30
- Completion
- 2023-10-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Flumazenil | Small molecule | — | — |
| Subject | Propofol | Small molecule | 6 mg/kg | — |
| Subject | Propofol | Small molecule | 8 mg/kg | — |
| Subject | Remimazolam | Small molecule | 0.3 mg/kg | — |
| Subject | Remimazolam | Small molecule | 0.7 mg/kg | — |
Indications
No indication recorded.