drugset / Trial / NCT06515314

HRYZ-T102 TCR-T Cell for AFP Positive Advanced HCC and Other Solid Tumors

NCT06515314 ↗

Phase 1 Recruiting 12 enrolled Shanghai Ruiliyuan Biotechnology Co., Ltd.
NaSingle-groupOpen-labelTreatment

Summary

This is a single arm, open-label, dose escalation clinical study to evaluate the safety and efficacy of HRYZ-T102 TCR-T Cell in patients with AFP positive advanced hepatocellular carcinoma and other solid tumors refractory to prior systematic treatments.

Timeline

Start
2024-10-17
Primary completion
2026-08-10
Completion
2027-08-10

Drugs

EvaluationDrugModalityDoseRoute
Subject HRYZ-T102 Cell therapy — Intravenous
Background Cyclophosphamide Other / unclassified 250 mg/m2 —
Background Fludarabine Small molecule 25 mg/m2 —