drugset / Trial / NCT06524323
A Randomized, Double-blinded, Self-controlled Clinical Study of Intralesional Injection of 5-fluorouracil Plus Triamcinolone for the Treatment of Refractory Nodular Prurigo
Phase 3
Not yet recruiting
60 enrolled
Second Affiliated Hospital, School of Medicine, Zhejiang University
RandomizedParallel-groupDouble-blindTreatment
Summary
Nodular pruritus is a chronic inflammatory skin disease manifested as individual or multiple highly keratotic nodules with severe itching. The goal of this clinical trial is to compare the efficacy and safety of treating refractory nodular pruritus with intralesional injections of 5-fluorouracil alone or 5-fluorouracil plus triamcinolone acetonide.
Timeline
- Start
- 2024-09-01
- Primary completion
- 2026-08-31
- Completion
- 2026-08-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Triamcinolone Acetonide | Other / unclassified | 2 ml | Other |
| Subject | fluorouracil | Small molecule | 4 ml | Other |