the Efficacy and Safety of Oliceridine Fumarate Injection for Acute Pain After Abdominal Surgery
Summary
The goal of this clinical trial is to learn if Oliceridine fumarate injection works to treat acute pain after abdominal surgery. It will also learn about the safety of Oliceridine fumarate injection. The main questions it aims to answer are: 1. Does Oliceridine fumarate injection works to treat acute pain after abdominal surgery? 2. Does Oliceridine fumarate injection lead to less adverse effect? Researchers will compare Oliceridine fumarate injection to a positive-drug (Sufentanil Citrate) to see if Oliceridine fumarate injection not inferior to sufentanil in the efficacy and safety for acute pain after abdominal surgery. Participants will: 1. Receive patient controlled analgesia treat using Oliceridine or sufentanil after surgery 2. Be followed up every 6 hours until 48 hours after surgery or before discharge
Timeline
- Start
- 2025-08
- Primary completion
- 2026-04
- Completion
- 2026-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Oliceridine | Other / unclassified | 0.4 mg/kg | — |
| Subject | Oliceridine | Other / unclassified | 0.6 mg/kg | — |
| Comparator | Sufentanil | Other / unclassified | 2 ug/kg | — |
Indications
No indication recorded.