drugset / Trial / NCT06536374

Folate Study in Men With Advanced Prostate Cancer

NCT06536374

Phase 2 Not yet recruiting 50 enrolled University of California, San Diego
RandomizedParallel-groupOpen-labelTreatment

Summary

The researchers hope to learn if Trimethoprim, 150mg taken daily for 3 months, is a safe and effective way to reduce folate levels at time of Androgen Deprivation Therapy (ADT) in men with advanced prostate cancer. This study will help find out what effects, good and/or bad, this drug has on people who take it and on its effect on the disease. The safety of this drug in humans has been tested in prior research studies; however, some side effects may not yet be known.

Timeline

Start
2026-06
Primary completion
2027-12
Completion
2027-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Trimethoprim Small molecule 150 mg

Indications