drugset / Trial / NCT06537310

A Dose-escalation Study of RO7567132 as Single Agent and in Combination With Atezolizumab in Participants With Advanced Solid Tumors

NCT06537310

Phase 1 Active not recruiting 34 enrolled Hoffmann-La Roche
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate the safety, pharmacokinetics (PK), pharmacodynamics (PD) and preliminary clinical activity of RO7567132 as single agent and in combination with atezolizumab. The study will enroll adult participants with selected locally advanced and/or metastatic solid tumors for whom standard therapy does not exist, or has proven to be ineffective or intolerable.

Timeline

Start
2024-09-16
Primary completion
2027-05-12
Completion
2027-08-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Atezolizumab Monoclonal antibody
Subject RO7567132 Unknown

Indications