A Study to Learn if the Study Medicines Called Itraconazole and Cyclosporine Change How the Body Processes the Other Study Medicine Called Danuglipron in Healthy Adults.

Phase 1 Completed 16 enrolled Pfizer

RandomizedSequentialOpen-labelTreatment

Summary

The purpose of this study is to see how single dose of cyclosporine and multiple doses of itraconazole affect the level of the study medicine danuglipron in the blood of healthy adult participants. The information from this study may inform how danuglipron will be used in the future with medicines like cyclosporine and itraconazole.

Timeline

Start: 2024-12-23
Primary completion: 2025-03-10
Completion: 2025-03-10

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Cyclosporine	Peptide	600 mg	Oral
Subject	Danuglipron	Small molecule	20 mg	Oral
Subject	Itraconazole	Small molecule	—	Oral

Indications

No indication recorded.