drugset / Trial / NCT06543043
A Study to Evaluate the Effects of Phenytoin and Itraconazole on Sonrotoclax (BGB-11417) in Healthy Volunteers
Non-randomizedParallel-groupOpen-labelBasic science
Summary
This is a single-center, open-label, parallel group study designed to investigate the effect of CYP3A induction and inhibition following multiple doses of phenytoin (Part A) and itraconazole (Part B), respectively, on the pharmacokinetics of sonrotoclax in healthy volunteers.
Timeline
- Start
- 2024-08-19
- Primary completion
- 2024-10-08
- Completion
- 2024-11-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Itraconazole | Small molecule | — | Oral |
| Subject | Phenytoin | Unknown | — | Oral |
| Subject | Sonrotoclax | Other / unclassified | — | Oral |
Indications
No indication recorded.