drugset / Trial / NCT06561698
High-dose Dual Therapy and Minocycline-cotaining Quadruple Therapy for Helicobacter Pylori Infection
Non-randomizedParallel-groupOpen-labelTreatment
Summary
This study is a multicentra, prospective study. The enrolled patients are HP positive. They are diagnosed as HP positive by rapid urease test and/or 13C urea breath test. According to the declaration of Helsinki, 200 patients will be included in this study. After obtaining the written informed consent of the patients, HP culture and drug sensitivity test will be conducted on all the selected patients with the success rate, adverse reactions, compliance, antibiotic resistance of HP and its impact on HP eradication.
Timeline
- Start
- 2024-08-21
- Primary completion
- 2026-08-30
- Completion
- 2026-08-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Amoxicillin | Other / unclassified | — | — |
| Subject | Bismuth Potassium Citrate | Unknown | — | — |
| Subject | Metronidazole | Small molecule | — | — |
| Subject | Minocycline | Small molecule | — | — |
| Subject | Vonoprazan | Other / unclassified | — | — |