drugset / Trial / NCT06566508

Effectiveness of Asiaticoside as Intracanal Medication on Infectious/Inflammatory Contents in Teeth With Apical Periodontitis

NCT06566508

Phase 2/3 Recruiting 36 enrolled Mansoura University
RandomizedCrossoverDouble-blindTreatment

Summary

The objective of this study is to investigate \"clinically\" the effectiveness of Asiaticoside based intracanal medication compared to the commonly used intracanal medicaments (calcium hydroxide Ca(OH)2 and Ledermix) on the levels of bacteria and inflammatory cytokines in root canals and periradicular tissues of teeth with apical periodontitis.

Timeline

Start
2023-11-20
Primary completion
2024-06-05
Completion
2025-03-03

Drugs

EvaluationDrugModalityDoseRoute
Comparator Asiaticoside Small molecule Other
Comparator Calcium Hydroxide Other / unclassified Other
Comparator Leddermix Unknown Other

Indications

No indication recorded.