drugset
Drugs / Calcium Hydroxide
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Calcium Hydroxide

also known as Ca(OH)2 · Calcium hydroxide (Ca(OH)₂) · Metapaste · Calacept · Calcarea caustica · Calcium hydroxide solution · Dycal · Dycal\_ Ivory · +6 more

Other / unclassified

Developed for
periapical periodontitis · dental pulp necrosis · acute apical periodontitis · dental caries · dental pulp disorder · tooth disorder · neuropathy, painful · periodontal disorder
+8 more · pulpitis · suppurative periapical periodontitis · chronic apical periodontitis · chronic pain syndrome · dental pulp calcification · exposure, dental pulp · lichen planus, oral · periodontitis
Investigated by
Cairo University · Al-Azhar University · Pakistan Institute of Medical Sciences · Altamash Institute of Dental Medicine · Altinbas University · Azad University of Medical Sciences
+15 more · College of Physicians and Surgeons Pakistan · Didem Sakaryali · Dr. D. Y. Patil Dental College & Hospital · Ege University · Faiz ur rahman · Future University in Egypt · HITEC-Institute of Medical Sciences · Istanbul University · Jordan University of Science and Technology · Mahmoud M Saadoon · Mahy Abdel Raouf Aly Kamar · Minia University · Mustafa Kemal University · São Paulo State University · rayan rabie dahab

Trials 23

today NCT07239739 · not/applicable NCT07585721 · not/applicable NCT07571837 · not/applicable NCT07867951 · not/applicable NCT07071675 · not/applicable NCT07141459 · not/applicable NCT06625645 · not/applicable NCT07123792 · not/applicable NCT06653608 · not/applicable NCT06253247 · not/applicable NCT06632015 · not/applicable NCT06174909 · not/applicable NCT04900571 · Ph 4 NCT04319575 · Ph 2/3 NCT03064191 · not/applicable NCT05581706 · not/applicable NCT03403985 · not/applicable NCT03084601 · Ph 4 NCT03009006 · not/applicable NCT02824601 · Ph 2 NCT03426046 · Ph 4 NCT03606681 · not/applicable NCT01730287 · Ph 2
201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 22 trials
Phase 2 NCT02824601 Feb 2015 → Apr 2016 tooth disorder São Paulo State University Completed No outcome recorded
Phase 2 NCT01730287 May 2010 → Dec 2012 dental pulp necrosis Azad University of Medical Sciences Unknown No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT04319575 Dec 2018 → Apr 2020 suppurative periapical periodontitis Dr. D. Y. Patil Dental College & Hospital Unknown No outcome recorded
Phase 43 trials
Phase 4 NCT04900571 Jan → May 2021 neuropathy, painful, pulpitis Altamash Institute of Dental Medicine Completed No outcome recorded
Phase 4 NCT03084601 Mar 2017 → Jan 2018 dental pulp necrosis Mahmoud M Saadoon Completed No outcome recorded
Phase 4 NCT03426046 Nov 2013 → Apr 2016 dental caries Didem Sakaryali Completed No outcome recorded
Phase not applicable17 trials
— NCT07239739 Jun → Nov 2026 expected periapical periodontitis Faiz ur rahman Not yet recruiting No outcome recorded
— NCT07585721 Jun 2026 → Feb 2027 expected periapical periodontitis Future University in Egypt Recruiting No outcome recorded
— NCT07571837 Feb 2026 → Jan 2027 expected periapical periodontitis Al-Azhar University Recruiting No outcome recorded
— NCT07867951 Sep 2025 → May 2026 overdue periapical periodontitis College of Physicians and Surgeons Pakistan Recruiting No outcome recorded
— NCT07071675 Sep 2025 → Aug 2026 overdue type 2 diabetes mellitus Minia University Not yet recruiting No outcome recorded
— NCT07141459 Aug 2025 → Sep 2026 overdue periapical periodontitis Al-Azhar University Recruiting No outcome recorded
— NCT06625645 Jan → May 2025 overdue dental pulp necrosis, periapical periodontitis Mahy Abdel Raouf Aly Kamar Not yet recruiting No outcome recorded
— NCT07123792 Jun 2024 → May 2025 periodontal disorder HITEC-Institute of Medical Sciences Completed No outcome recorded
— NCT06653608 Apr → Sep 2024 acute apical periodontitis, dental pulp necrosis Pakistan Institute of Medical Sciences Completed No outcome recorded
— NCT06253247 Apr → Jun 2024 — Cairo University Unknown No outcome recorded
Comparator or background therapy54 trials
Phase 0 NCT07821866 Comparator Apr 2026 → Apr 2027 expected — Future University in Egypt Active not recruiting No outcome recorded
Phase 0 NCT07603934 Comparator Dec 2025 → Aug 2026 overdue dental pulp necrosis Cairo University Recruiting No outcome recorded
Phase 0 NCT07101029 Comparator Aug 2025 → Jul 2026 overdue acute apical periodontitis Cairo University Not yet recruiting No outcome recorded
Phase 0 NCT07423663 Comparator Sep 2024 → Mar 2026 overdue periapical periodontitis Suez Canal University Active not recruiting No outcome recorded
Phase 0 NCT05687760 Comparator Feb 2023 — Cairo University Unknown No outcome recorded

Evidence & citations 18 cited values

Every value below carries the sentence it was read from. 78 sources stand behind the page.

FieldValueCited text
Known as Calcium Hydroxide “It contains calcium hydroxide, hyaluronic acid, Umbelliferone and Oligomeric Proanthocyanidins.” NCT04673916 ↗
73

“using Chitosan mixed with calcium hydroxide or Triple Antibiotic Paste at 3,6 and 12 months.” NCT04319575 ↗

“between intracanal medicaments Nitrofurantoin and Calcium Hydroxide Paste” NCT04900571 ↗

“Partial pulpotomy treatment with Calcium Hydroxide” NCT03426046 ↗

NCT03723980 ↗

NCT07371416 ↗

NCT06466538 ↗

NCT05222243 ↗

NCT07183514 ↗

NCT07437612 ↗

NCT06625645 ↗

Show 63 more sources
Known as Ca(OH)2 “Use of 2% Chlorhexidine (CHX) as Intracanal Medicament in Endodontic Emergencies and to Compare Its Use and Effectiveness With CaOH2 (CH) Calcium Hydroxide Paste” NCT03700788 ↗
17

“Experimental group Ca (OH) 2 ( Ca (OH) 2with nanosilver suspension and comparison group Ca (OH) 2 with sterile water” NCT04213716 ↗

“Calcium hydroxide (Ca(OH)2) is considered as a universal intracanal medicament for this purpose .” NCT05021809 ↗

“Calcium hydroxide (Ca(OH)2) has been used extensively in dentistry since the 1920s (17).” NCT06453304 ↗

“Calcium hydroxide [Ca(OH)2] is the most commonly used intracanal medication.” NCT06466538 ↗

“Calcium Hydroxide (Ca(OH)2) Intracanal Medication” NCT07821866 ↗

“Calcium Hydroxide (Ca(OH)2) Intracanal Medication” NCT07826091 ↗

“Calcium Hydroxide (Ca(OH)2) Intracanal Medication” NCT07641933 ↗

“intracanal medication of Ca(OH)2 paste” NCT05666089 ↗

“Drug: Calcium Hydroxide (Ca(OH)2)” NCT07495605 ↗

“Calcium Hydroxide (Ca(OH)2)” NCT07340944 ↗

Show 7 more sources
Known as Calacept “Calcium hydroxide (Calacept)” NCT04000854 ↗
Known as Calcarea caustica ChEMBL registry synonym — accepted as the source's own label CHEMBL2106388 ↗
Known as Calcium hydroxide (Ca(OH)₂) ClinicalTrials.gov intervention name — accepted as the source's own label NCT07262554 ↗
2

NCT07585721 ↗

NCT03403985 ↗
Known as Calcium hydroxide solution ChEMBL registry synonym — accepted as the source's own label CHEMBL2106388 ↗
Known as Dycal “calcium hydroxide( Dycal ® Dentsply Caulk )was applied using calcium hydroxide applicator followed by glass ionomer and then composite resin as a final restoration” NCT03631277 ↗
Known as Dycal\_ Ivory “For Group I patients, Calcium hydroxide (Dycal\_ Ivory,Dentsply Caulk, Dentsply, L.D. Caulk, Milford, DE,USA ) was used.” NCT06807320 ↗
Known as E-526 ChEMBL registry synonym — accepted as the source's own label CHEMBL2106388 ↗
Known as INS NO.526 ChEMBL registry synonym — accepted as the source's own label CHEMBL2106388 ↗
Known as INS-526 ChEMBL registry synonym — accepted as the source's own label CHEMBL2106388 ↗
Known as Lime hydrate ChEMBL registry synonym — accepted as the source's own label CHEMBL2106388 ↗
Known as Lime water ChEMBL registry synonym — accepted as the source's own label CHEMBL2106388 ↗
Known as Metapaste “intracanal medication of calcium hydroxide paste (metapaste)” NCT05666089 ↗
1

“Metapaste [calcium hydroxide paste (control group)]” NCT06342830 ↗
Known as Slaked lime ChEMBL registry synonym — accepted as the source's own label CHEMBL2106388 ↗
Action Inhibit “Ca(OH)2 also inactivates lipopolysaccharide so it can assist in periapical tissue repair (19).” NCT06453304 ↗
Modality Other / unclassified “Inorganic compound (CA(OH)2.” NCT02492841 ↗
Route Other “calcium hydroxide intracanal medication alone for 2 weeks period” NCT03009006 ↗