drugset / Trial / NCT06821763

To Measure Post Operative Pain Severity by Using Two Different Intra Canal Medicaments Calcium Hydroxide and Triple Antibiotic Paste in Teeth with Single Roots and Periapical Disease Called Apical Periodontitis

NCT06821763

Phase 2/3 Not yet recruiting 180 enrolled Komal Ashraf Khan
RandomizedParallel-groupTriple-blindTreatment

Summary

* The aim of this study is to compare post operative pain effectiveness between two most commonly available intra canal medicaments that are Triple Antibiotic Paste and Calcium Hydroxide during root canal treatment of single rooted teeth with symptomatic apical periodontitis. * Patients visiting OPD will be selected after fulfilment of inclusion criteria and randomly divided into two groups i.e group A patients receiving calcium hydroxide and group B with patients receiving Triple Antibiotic Paste as intra canal medicaments * Patient will be called at 48hrs 72hrs and 96hrs postoperatively. * Effectiveness of intra canal medicaments will be measured as no mild moderate severe on visual analogue scale(VAS).

Timeline

Start
2025-05-01
Primary completion
2025-10-01
Completion
2025-11-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Calcium Hydroxide Other / unclassified Other
Comparator Ciprofloxacin Small molecule Other
Comparator Metronidazole Small molecule Other
Comparator Minocycline Small molecule Other

Indications