drugset / Trial / NCT07603934
The Effect of Different Intra-canal Medications on Postoperative Pain
Phase 0
Recruiting
111 enrolled
Cairo University
Egyptian Russian University · collabFayoum University · collab
RandomizedParallel-groupDouble-blindTreatment
Summary
The aim of this study is to assess the effect of ibuprofen, nitrofurantoin, and calcium hydroxide on postoperative pain after endodontic treatment of necrotic mandibular posterior teeth Research question/hypothesis: In patients with necrotic pulps in their mandibular posterior teeth, there would be no difference in the incidence and/or severity of postoperative pain after the use of ibuprofen, nitrofurantoin, or calcium hydroxide intracanal medications. The study will evaluate postoperative pain after using either of the tested drugs as an intracanal medication amidst visits. of endodontic treatment in cases where pulp necrosis is confirmed.
Timeline
- Start
- 2025-12-15
- Primary completion
- 2026-08-15
- Completion
- 2026-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Calcium Hydroxide | Other / unclassified | — | Other |
| Subject | Ibuprofen | Small molecule | — | Other |
| Subject | Nitrofurantoin | Unknown | — | Other |