drugset / Trial / NCT07423663

Antimicrobial Effect of Calcium Silicate and Pectin as Intracanal Medications in Necrotic Teeth With Periapical Lesions

NCT07423663

Phase 0 Active not recruiting 63 enrolled Suez Canal University University of Leeds · collab
RandomizedParallel-groupQuadruple-blindBasic science

Summary

It is tackling antimicrobial resistance in endodontics, specifically comparing different intracanal medications used in root canal treatment. Given the growing concern over resistant bacterial strains, our study aims to evaluate the effectiveness of various medicaments in eliminating endodontic pathogens while minimising the risk of resistance development. By integrating microbiological analysis and clinical relevance, our research seeks to provide evidence-based recommendations for optimising intracanal disinfection protocols and improving treatment outcomes in endodontic infections.

Timeline

Start
2024-09-01
Primary completion
2026-03-10
Completion
2026-04-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Bio-C Temp Other / unclassified
Comparator Calcium Hydroxide Other / unclassified
Subject Pectin Other / unclassified