drugset / Trial / NCT07423663
Antimicrobial Effect of Calcium Silicate and Pectin as Intracanal Medications in Necrotic Teeth With Periapical Lesions
RandomizedParallel-groupQuadruple-blindBasic science
Summary
It is tackling antimicrobial resistance in endodontics, specifically comparing different intracanal medications used in root canal treatment. Given the growing concern over resistant bacterial strains, our study aims to evaluate the effectiveness of various medicaments in eliminating endodontic pathogens while minimising the risk of resistance development. By integrating microbiological analysis and clinical relevance, our research seeks to provide evidence-based recommendations for optimising intracanal disinfection protocols and improving treatment outcomes in endodontic infections.
Timeline
- Start
- 2024-09-01
- Primary completion
- 2026-03-10
- Completion
- 2026-04-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bio-C Temp | Other / unclassified | — | — |
| Comparator | Calcium Hydroxide | Other / unclassified | — | — |
| Subject | Pectin | Other / unclassified | — | — |