drugset / Trial / NCT06572813

Bortezomib Combined with PD-1 MAb and MFOLFIRINOX for Metastatic Pancreatic Cancer

NCT06572813

Phase 1/2 Recruiting 63 enrolled Zhejiang University
Non-randomizedSequentialOpen-labelTreatment

Summary

This is an single-center, prospective, open-label clinical trial, to explore the safty and efficacy of combination of Bortezomib, Sindilizumab, and mFOLFIRINOX Chemotherapy (oxaliplatin, fluorouracil, irinotecan, leucovorin) in metastatic pancreatic cancer

Timeline

Start
2024-11-15
Primary completion
2026-09-01
Completion
2028-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Bortezomib Small molecule
Subject Irinotecan Small molecule
Subject Leucovorin Small molecule
Subject Oxaliplatin Small molecule
Subject Sintilimab Monoclonal antibody
Subject fluorouracil Small molecule