drugset / Trial / NCT06575699

Rectus Sheath Block for Analgesia After Gynecological Laparotomy

NCT06575699

Phase 4 Completed 90 enrolled Duke University
Non-randomizedParallel-groupOpen-labelPrevention

Summary

Thirty subjects undergoing laparotomy for Gynecologic oncology surgery will be prospectively enrolled and will receive a bilateral rectus sheath block (RSB) under ultrasound guidance using 133 mg liposomal bupivacaine and 20 ml bupivacaine 0.25% per side. Cases will be matched in a 1:2 ratio by age, race, insurance status and duration of surgery with historical controls who received postoperative analgesia using thoracic epidural analgesia.

Timeline

Start
2024-10-10
Primary completion
2025-11-28
Completion
2025-11-28

Drugs

EvaluationDrugModalityDoseRoute
Subject Bupivacaine Other / unclassified 0.25 % Other
Subject Bupivacaine Other / unclassified 0.625 % Other
Subject Bupivacaine Other / unclassified 20 ml Other
Subject Bupivacaine Other / unclassified 133 mg Other
Comparator Hydromorphone Other / unclassified 10 ug/ml Other

Indications

No indication recorded.