drugset / Trial / NCT06579690
Use of Preoperative Sodium Bicarbonate Among Women With Obstructed Labor
Phase 3
Completed
472 enrolled
Busitema University
Cures Within Reach · collabOpen Philanthropy · collabOslo University Hospital · collabUniversity of Liverpool · collab
RandomizedParallel-groupTriple-blindTreatment
Summary
The goal of this clinical trial is to determine a universal safe and effective dose of sodium bicarbonate for use among women with Obstructed labour to treat acidosis. It will also learn about the safety of sodium bicarbonate drug among women with Obstructed labour. Researchers will compare sodium bicarbonate drug to normal saline (a look-alike solution) to see if sodium bicarbonate works to treat acidosis. Participants will receive sodium bicarbonate solution or a placebo up to two doses, four hours apart.
Timeline
- Start
- 2025-05-06
- Primary completion
- 2026-04-04
- Completion
- 2026-04-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | sodium bicarbonate | Diagnostic / imaging agent | 8.4 g | Intravenous |
| Subject | sodium bicarbonate | Diagnostic / imaging agent | 12.6 g | Intravenous |
| Subject | sodium bicarbonate | Diagnostic / imaging agent | 16.8 g | Intravenous |