drugset / Trial / NCT06588907
Pain Palliation in Forearm Fractures in the Emergency Department
RandomizedParallel-groupDouble-blindTreatment
Summary
The aim is to evaluate the success of reduction procedures and pain palliation in patients with forearm fractures undergoing reduction under procedural sedation-analgesia (PSA) and ultrasound (US)-guided infraclavicular nerve block (ICB) in the emergency department.
Timeline
- Start
- 2024-06-01
- Primary completion
- 2024-12-01
- Completion
- 2024-12-15
Publications
- Background Fauteux-Lamarre E, Burstein B, Cheng A, Bretholz A. Reduced Length of Stay and Adverse Events Using Bier Block for Forearm Fracture Reduction in the Pediatric Emergency Department. Pediatr Emerg Care. 2019 Jan;35(1):58-62. doi: 10.1097/PEC.0000000000000963.
- Results Tekin E, Aydin ME, Turgut MC, Karagoz S, Ates I, Ahiskalioglu EO. Can ultrasound-guided infraclavicular block be an alternative option for forearm reduction in the emergency department? A prospective randomized study. Clin Exp Emerg Med. 2021 Dec;8(4):307-313. doi: 10.15441/ceem.20.136. Epub 2021 Dec 31.
- Results Kukreja P, Kofskey AM, Ransom E, McKenzie C, Feinstein J, Hudson J, Kalagara H. Comparison of Supraclavicular Regional Nerve Block Versus Infraclavicular Regional Nerve Block in Distal Radial Open Reduction and Internal Fixation: A Retrospective Case Series. Cureus. 2022 Apr 12;14(4):e24079. doi: 10.7759/cureus.24079. eCollection 2022 Apr.
- Sarcan E, Erdem AB, Uysal SB, Duman E, Cebeci Z, Arik E. Pain management with ketamine procedural sedation and infraclavicular block for forearm fracture in the emergency department. Am J Emerg Med. 2025 Oct;96:256-263. doi: 10.1016/j.ajem.2025.07.012. Epub 2025 Jul 16.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Bupivacaine | Other / unclassified | 0.25 % | Other |
| Comparator | Bupivacaine | Other / unclassified | 20 ml | Other |
| Comparator | Ketamine | Small molecule | 0.5 mg/kg | Intravenous |
| Comparator | Ketamine | Small molecule | 1 mg/kg | Intravenous |