drugset / Trial / NCT06612814
PARP Inhibitor With CDK4/ 6 Inhibitor and Endocrine Therapy in HR+/ HER2-Advanced Breast Cancer
Phase 3
Active not recruiting
307 enrolled
Zhimin Shao
Affiliated Hospital of Nantong University · collabChongqing University Cancer Hospital · collabFirst Affiliated Hospital Xi'an Jiaotong University · collabFirst Hospital of China Medical University · collabFujian Medical University Union Hospital · collabLiaoning Cancer Hospital & Institute · collabNingbo Medical Center Lihuili Hospital · collabNorthern Jiangsu People's Hospital · collabPeking University Cancer Hospital & Institute · collabShanghai 6th People's Hospital · collabShanghai First Maternity and Infant Hospital · collabSun Yat-sen University · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
This study is a prospective, open-label, phase III clinical study for patients with HR+/HER2- advanced breast cancer.
Timeline
- Start
- 2024-09-01
- Primary completion
- 2027-10-30
- Completion
- 2028-04-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Fluzoparib | Small molecule | — | — |
| Background | Dalpiciclib | Small molecule | — | — |
| Background | Fulvestrant | Small molecule | — | — |