Dexmedetomidine Dosage for Postoperative Delirium and Cognitive Function in Elderly TKA Patients

Summary

This study aims to evaluate the efficacy of dexmedetomidine in reducing the incidence of postoperative delirium and cognitive dysfunction in elderly patients undergoing total knee arthroplasty (TKA). The study will compare the outcomes of patients receiving dexmedetomidine to those receiving a standard anesthetic or sedative, focusing on factors such as patient characteristics, surgical duration, and postoperative care. The research will explore the potential neuroprotective effects of dexmedetomidine and its ability to mitigate the risks associated with anesthesia and surgery in vulnerable elderly populations.

Timeline

Start

2024-07-01

Primary completion

2024-10-15

Completion

2024-11-01

Drugs

Indications