drugset / Trial / NCT06619847
A Study Evaluating Efficacy and Safety of VX-993 for Acute Pain After a Bunionectomy
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The purpose of this study is to evaluate the efficacy, safety, tolerability and pharmacokinetics of VX-993 in treating acute pain after a bunionectomy.
Timeline
- Start
- 2024-10-29
- Primary completion
- 2025-05-27
- Completion
- 2025-05-27
Outcome
Missed primary endpoint
release “Treatment with the selective NaV1.8 pain signal inhibitor VX-993 after bunionectomy surgery did not meet the primary endpoint” vrtx.com ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Acetaminophen | Small molecule | — | Oral |
| Comparator | Hydrocodone | Unknown | — | Oral |
| Subject | VX-993 | Unknown | — | Oral |
Indications
No indication recorded.