drugset / Trial / NCT06624059

A Study to See How Well and How Safely Different Treatments Work in a Group of Participants With Non-Small Cell Lung Cancer (NSCLC)

NCT06624059

Phase 1/2 Active not recruiting 11 enrolled Hoffmann-La Roche
NaSingle-groupOpen-labelTreatment

Summary

The objective of this study is to explore the safety of alectinib in combination with chemotherapy in participants with resectable NSCLC. Cohort B1 is a phase II cohort that will assess the safety of alectinib in combination with up to four cycles of platinum-based chemotherapy in the adjuvant setting post complete surgical resection.

Timeline

Start
2024-11-18
Primary completion
2026-08-28
Completion
2026-08-28

Drugs

EvaluationDrugModalityDoseRoute
Subject Alectinib Small molecule Oral
Background Carboplatin Small molecule Intravenous
Background Cisplatin Other / unclassified Intravenous
Background Pemetrexed Small molecule Intravenous