drugset / Trial / NCT06624085

A Study Evaluating the Safety and Efficacy of Glofitamab + Gemcitabine + Oxaliplatin in U.S. Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma

NCT06624085

Phase 1 Recruiting 50 enrolled Hoffmann-La Roche
NaSingle-groupOpen-labelTreatment

Summary

The purpose of the study is to evaluate glofitamab + gemcitabine + oxaliplatin in participants in the United States, including under-represented racial and ethnic populations, that have relapsed or refractory (R/R) diffuse large B-cell lymphoma (DLBCL).

Timeline

Start
2025-04-28
Primary completion
2030-03-31
Completion
2030-03-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Gemcitabine Small molecule Intravenous
Subject Glofitamab Monoclonal antibody Intravenous
Subject Oxaliplatin Small molecule Intravenous
Background Obinutuzumab Monoclonal antibody Intravenous
Background Tocilizumab Monoclonal antibody Intravenous

Indications