drugset / Trial / NCT06625814

A Study of Levothyroxine and Enlicitide Decanoate (MK-0616) in Healthy Adult Participants (MK-0616-028)

NCT06625814

Phase 1 Completed 28 enrolled Merck Sharp & Dohme LLC Celerion · collab
RandomizedCrossoverOpen-labelBasic science

Summary

Levothyroxine (T4) is a man-made thyroid hormone used to treat certain thyroid conditions. After taking levothyroxine, a person's body changes it to triiodothyronine (T3). The amount of levothyroxine in a person's blood must be carefully controlled to maintain proper function. Enlicitide decanoate was designed to lower the amount of cholesterol in a person's blood. Researchers want to learn about levothyroxine when taken at the same time with enlicitide decanoate. They want to: * Measure a person's blood to find out if the amount of levothyroxine in the blood is the same when levothyroxine is taken alone or with enlicitide decanoate * Learn about the safety of levothyroxine when taken alone or with enlicitide decanoate and if people tolerate it

Timeline

Start
2024-07-08
Primary completion
2024-08-19
Completion
2024-09-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Enlicitide Decanoate Unknown
Subject Levothyroxine Other / unclassified Oral

Indications

No indication recorded.