drugset / Trial / NCT06634355

Placental Transfer of Sugammadex in the Human Placental Perfusion Model

NCT06634355

Enrolling by invitation 16 enrolled Universitaire Ziekenhuizen KU Leuven
NaSingle-groupOpen-labelBasic science

Summary

Preclinical research raised concern regarding the foetal effects of using sugammadex during pregnancy. However, to the best of our knowledge, the placental transfer of sugammadex has never been measured. As these data would be critical in assessing the foetal effects after maternal administration of sugammadex, it is warranted to measure the placental transfer of sugammadex. The aim of this project is to measure the placental transfer of sugammadex in the human placenta by using the ex vivo human placenta perfusion model.

Timeline

Start
2025-03-17
Primary completion
2026-09
Completion
2026-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Sugammadex Other / unclassified

Indications