Age-related Changes in Retinal Oxygen Extraction in Healthy Subjects

Summary

It has been found that several systemic and ocular diseases are associated with impaired retinal oxygen extraction. In the present study, retinal oxygen extraction will be measured in different age groups in order to identify age related changes in otherwise healthy subjects. In addition, the study will explore short-term changes in retinal metabolism induced by breathing pure oxygen. Measurements will be performed with dynamic vessel analyzer and laser speckle flowgraphy to evaluate retinal blood flow and retinal oxygen saturation, in order to calculate retinal oxygen extraction.

Timeline

Start

2024-09-30

Primary completion

2025-12-31

Completion

2026-01-31

Drugs

Indications

No indication recorded.