drugset / Trial / NCT06649292

SHR-A1904 Compared With Investigator's Choice of Therapy in Claudin18.2 Positive Patitens With Second-line Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

NCT06649292

Phase 3 Recruiting 524 enrolled Shanghai Hengrui Pharmaceutical Co., Ltd.
RandomizedParallel-groupOpen-labelTreatment

Summary

The study evaluated the overall survival (OS) of SHR-A1904 versus investigator-selected treatment in second-line CLDN18.2-positive advanced GC/GEJC patients

Timeline

Start
2024-11-22
Primary completion
2027-09-20
Completion
2028-03-20

Drugs

EvaluationDrugModalityDoseRoute
Comparator Docetaxel Small molecule
Comparator Irinotecan Small molecule
Comparator Paclitaxel Small molecule
Subject SHR-A1904 Unknown