drugset / Trial / NCT06656962

The Efficacy and Safety of Treatment with Telitacicept in Antineutrophil Cytoplasmic Antibody-associated Nephritis (AAGN)

NCT06656962

Phase 1/2 Active not recruiting 15 enrolled Renmin Hospital of Wuhan University
NaSingle-groupOpen-labelTreatment

Summary

This study is a prospective, single-arm, open-label exploratory clinical study conducted in subjects with ANCA-associated nephritis (AAGN), aiming to evaluate the efficacy and safety of Telitacicept in the treatment of AAGN.

Timeline

Start
2024-10-10
Primary completion
2025-12-30
Completion
2026-10-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Telitacicept Protein / enzyme biologic 160 mg
Background Cyclophosphamide Other / unclassified 0.75 g Intravenous
Background Methylprednisolone Other / unclassified 500 mg
Background Prednisone Other / unclassified 1 mg/kg