The Use of 5-ALA in Paediatric Patients With High Grade Brain Tumours

Summary

The aim of the study is to examine the safety and feasibility of using 5-ALA in children who have MRI scans showing an aggressive looking brain tumour. It will also study if 5-ALA can help the surgeon achieve maximal tumour removal and discriminate between normal brain tissue and tumour. Patients will be between 3-18 years (inclusive) and all patients will receive 5-ALA 3-6 hours prior to resection surgery.

Timeline

Start

2025-03-25

Primary completion

2026-06-30

Completion

2026-12-30

Drugs

Indications