drugset / Trial / NCT06684106

Ursodeoxycholic Acid Attenuates Statin-Induced Impaired Glucose Tolerance

NCT06684106

RandomizedParallel-groupDouble-blindPrevention

Summary

The purpose of this clinical trial is to understand whether the drug Ursodeoxycholic acid (UDCA) can prevent glucose intolerance in participants with hyperlipidemia who are taking statins. It will also assess the safety of UDCA. The primary questions it aims to answer are: * Will UDCA reduce the incidence of glucose intolerance in participants taking oral statins? * Will the use of UDCA decrease other adverse events in patients taking oral statins? Participants will: * Take Atorvastatin combined with UDCA or a placebo daily for 6 months * Have follow-up visits on day 40, day 110, and day 180 Have their examination indicators recorded.

Timeline

Start
2024-11-25
Primary completion
2026-11-11
Completion
2027-06-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Ursodeoxycholic Acid Small molecule 500 mg