drugset / Trial / NCT06688656

Neoadjuvant Chemotherapy Sequentially Combined with Sintilimab in Resectable EGFR-Mutant NSCLC

NCT06688656 ↗

Phase 2 Not yet recruiting 30 enrolled Shanghai Chest Hospital
NaSingle-groupOpen-labelTreatment

Summary

This study is a prospective, single-arm, single-center Phase II trial, aiming to investigate efficacy and safety of neoadjuvant chemotherapy sequentially combined with sintilimab in resectable EGFR-mutant stage II-IIIB non-squamous NSCLC patients

Timeline

Start
2025-03-31
Primary completion
2026-03-31
Completion
2028-03-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Carboplatin Small molecule — Intravenous
Subject Pemetrexed Small molecule 500 mg/m2 Intravenous
Subject Sintilimab Monoclonal antibody 200 mg Intravenous

Indications