drugset / Trial / NCT06689085

52 Week Study + 24-Month Long-Term Extension of Safety, PK, & Efficacy of XYOSTED® for Testosterone Replacement in Male Adolescents With Hypogonadism

NCT06689085

Phase 3 Recruiting 100 enrolled Halozyme Therapeutics
NaSingle-groupOpen-labelTreatment

Summary

This is a 52-week open label single arm study + 24-Month long-term safety extension to investigate the effects of XYOSTED, as testosterone replacement therapy, on adolescent males with either primary or secondary hypogonadism. The study aims to determine the effectiveness of XYOSTED measured by continuation or induction of puberty in addition to XYOSTED dosage, safety and testosterone levels.

Timeline

Start
2025-03-07
Primary completion
2028-03
Completion
2030-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Testosterone Enanthate Small molecule 25 mg
Subject Testosterone Enanthate Small molecule 50 mg
Subject Testosterone Enanthate Small molecule 75 mg
Subject Testosterone Enanthate Small molecule 100 mg

Indications