drugset / Trial / NCT06696625
Transcutaneous Auricular Vagus Nerve Stimulation in Dry Eye
RandomizedParallel-groupTriple-blindTreatment
Summary
Objective: To evaluate the effect of transcutaneous auricular vagus nerve stimulation (taVNS) for the patients with dry eye disease. Methods: The investigators enrolled 256 patients at Beijing Tongren Hospital. Patients completed questionnaires at baseline, 1 month, 3 months, and 6 months. OSDI score, TBUT, Schirmer I, CFS, SF36, DEQ5, and psychological status to evaluate the therapeutic effects. A difference of P \< 0.05 was considered statistically significant.
Timeline
- Start
- 2021-07-01
- Primary completion
- 2025-11-01
- Completion
- 2025-12-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Background | Sodium Hyaluronate | Other / unclassified | 0.1 % | Other |